Dissolve-E: AWMF Guideline Registry
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## : SIGN Grade of Recommendation - TTL Representation

Active as of 2026-01-29

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    @prefix fhir: <http://hl7.org/fhir/> .
    @prefix owl: <http://www.w3.org/2002/07/owl#> .
    @prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
    @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
    @prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

    # - resource -------------------------------------------------------------------

     a fhir:CodeSystem ;
      fhir:nodeRole fhir:treeRoot ;
      fhir:id [ fhir:v "cs-sign-grade-of-recommendation"] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem cs-sign-grade-of-recommendation</b></p><a name=\"cs-sign-grade-of-recommendation\"> </a><a name=\"hccs-sign-grade-of-recommendation\"> </a><p>This case-insensitive code system <code>http://fhir.awmf.org/awmf.ig/CodeSystem/cs-sign-grade-of-recommendation</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>Deutsch (German, de)</b></td></tr><tr><td style=\"white-space:nowrap\">A<a name=\"cs-sign-grade-of-recommendation-A\"> </a></td><td>Grade A</td><td>At least one meta-analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or a body of evidence consisting principally of studies rated as 1+, directly applicable to the target population, and demonstrating overall consistency of results.</td><td>Empfehlungsgrad A</td></tr><tr><td style=\"white-space:nowrap\">B<a name=\"cs-sign-grade-of-recommendation-B\"> </a></td><td>Grade B</td><td>A body of evidence including studies rated as 2++, directly applicable to the target population, and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 1++ or 1+.</td><td>Empfehlungsgrad B</td></tr><tr><td style=\"white-space:nowrap\">C<a name=\"cs-sign-grade-of-recommendation-C\"> </a></td><td>Grade C</td><td>A body of evidence including studies rated as 2+, directly applicable to the target population and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 2++.</td><td>Empfehlungsgrad C</td></tr><tr><td style=\"white-space:nowrap\">D<a name=\"cs-sign-grade-of-recommendation-D\"> </a></td><td>Grade D</td><td>Evidence level 3 or 4; or extrapolated evidence from studies rated as 2+; or consensus-based recommendation.</td><td>Empfehlungsgrad D</td></tr></table></div>"^^rdf:XMLLiteral ]
      ] ; #
      fhir:url [
    fhir:v "http://fhir.awmf.org/awmf.ig/CodeSystem/cs-sign-grade-of-recommendation"^^xsd:anyURI ;
    fhir:l <http://fhir.awmf.org/awmf.ig/CodeSystem/cs-sign-grade-of-recommendation>
      ] ; #
      fhir:version [ fhir:v "0.2.0"] ; #
      fhir:name [ fhir:v "SIGNGradeOfRecommendation"] ; #
      fhir:title [ fhir:v "SIGN Grade of Recommendation"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:experimental [ fhir:v false] ; #
      fhir:date [ fhir:v "2026-01-29T18:27:10+00:00"^^xsd:dateTime] ; #
      fhir:publisher [ fhir:v "AWMF e.V."] ; #
      fhir:contact ( [
    fhir:name [ fhir:v "AWMF e.V." ] ;
        ( fhir:telecom [
    fhir:system [ fhir:v "url" ] ;
    fhir:value [ fhir:v "https://www.awmf.org" ]     ] )
      ] ) ; #
      fhir:description [ fhir:v "CodeSystem representing the Scottish Intercollegiate Guidelines Network (SIGN) Grades of Recommendation."] ; #
      fhir:caseSensitive [ fhir:v false] ; #
      fhir:content [ fhir:v "complete"] ; #
      fhir:count [ fhir:v "4"^^xsd:nonNegativeInteger] ; #
      fhir:concept ( [
    fhir:code [ fhir:v "A" ] ;
    fhir:display [ fhir:v "Grade A" ] ;
    fhir:definition [
    fhir:v "At least one meta-analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or a body of evidence consisting principally of studies rated as 1+, directly applicable to the target population, and demonstrating overall consistency of results." ;
          ( fhir:extension [
            ( fhir:extension [
    fhir:url [
    fhir:v "lang"^^xsd:anyURI ;
    fhir:l fhir:lang           ] ;
    fhir:value [
    a fhir:Code ;
    fhir:v "de"           ]         ] [
    fhir:url [
    fhir:v "content"^^xsd:anyURI ;
    fhir:l fhir:content           ] ;
    fhir:value [
    a fhir:String ;
    fhir:v "Mindestens eine Metaanalyse, systematische Review oder RCT mit 1++ bewertet und direkt auf die Zielpopulation anwendbar; oder ein Evidenzkörper bestehend hauptsächlich aus Studien mit 1+ bewertet, direkt auf die Zielpopulation anwendbar und mit konsistenten Ergebnissen."           ]         ] ) ;
    fhir:url [
    fhir:v "http://hl7.org/fhir/StructureDefinition/translation"^^xsd:anyURI ;
    fhir:l <http://hl7.org/fhir/StructureDefinition/translation>         ]       ] )     ] ;
        ( fhir:designation [
    fhir:language [ fhir:v "de" ] ;
    fhir:value [ fhir:v "Empfehlungsgrad A" ]     ] )
      ] [
    fhir:code [ fhir:v "B" ] ;
    fhir:display [ fhir:v "Grade B" ] ;
    fhir:definition [
    fhir:v "A body of evidence including studies rated as 2++, directly applicable to the target population, and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 1++ or 1+." ;
          ( fhir:extension [
            ( fhir:extension [
    fhir:url [
    fhir:v "lang"^^xsd:anyURI ;
    fhir:l fhir:lang           ] ;
    fhir:value [
    a fhir:Code ;
    fhir:v "de"           ]         ] [
    fhir:url [
    fhir:v "content"^^xsd:anyURI ;
    fhir:l fhir:content           ] ;
    fhir:value [
    a fhir:String ;
    fhir:v "Evidenzkörper mit Studien bewertet als 2++, direkt auf die Zielpopulation anwendbar und mit konsistenten Ergebnissen; oder extrapolierte Evidenz aus Studien bewertet als 1++ oder 1+."           ]         ] ) ;
    fhir:url [
    fhir:v "http://hl7.org/fhir/StructureDefinition/translation"^^xsd:anyURI ;
    fhir:l <http://hl7.org/fhir/StructureDefinition/translation>         ]       ] )     ] ;
        ( fhir:designation [
    fhir:language [ fhir:v "de" ] ;
    fhir:value [ fhir:v "Empfehlungsgrad B" ]     ] )
      ] [
    fhir:code [ fhir:v "C" ] ;
    fhir:display [ fhir:v "Grade C" ] ;
    fhir:definition [
    fhir:v "A body of evidence including studies rated as 2+, directly applicable to the target population and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 2++." ;
          ( fhir:extension [
            ( fhir:extension [
    fhir:url [
    fhir:v "lang"^^xsd:anyURI ;
    fhir:l fhir:lang           ] ;
    fhir:value [
    a fhir:Code ;
    fhir:v "de"           ]         ] [
    fhir:url [
    fhir:v "content"^^xsd:anyURI ;
    fhir:l fhir:content           ] ;
    fhir:value [
    a fhir:String ;
    fhir:v "Evidenzkörper mit Studien bewertet als 2+, direkt auf die Zielpopulation anwendbar und mit konsistenten Ergebnissen; oder extrapolierte Evidenz aus Studien bewertet als 2++."           ]         ] ) ;
    fhir:url [
    fhir:v "http://hl7.org/fhir/StructureDefinition/translation"^^xsd:anyURI ;
    fhir:l <http://hl7.org/fhir/StructureDefinition/translation>         ]       ] )     ] ;
        ( fhir:designation [
    fhir:language [ fhir:v "de" ] ;
    fhir:value [ fhir:v "Empfehlungsgrad C" ]     ] )
      ] [
    fhir:code [ fhir:v "D" ] ;
    fhir:display [ fhir:v "Grade D" ] ;
    fhir:definition [
    fhir:v "Evidence level 3 or 4; or extrapolated evidence from studies rated as 2+; or consensus-based recommendation." ;
          ( fhir:extension [
            ( fhir:extension [
    fhir:url [
    fhir:v "lang"^^xsd:anyURI ;
    fhir:l fhir:lang           ] ;
    fhir:value [
    a fhir:Code ;
    fhir:v "de"           ]         ] [
    fhir:url [
    fhir:v "content"^^xsd:anyURI ;
    fhir:l fhir:content           ] ;
    fhir:value [
    a fhir:String ;
    fhir:v "Evidenzlevel 3 oder 4; oder extrapolierte Evidenz aus Studien bewertet als 2+; oder konsensbasierte Empfehlung."           ]         ] ) ;
    fhir:url [
    fhir:v "http://hl7.org/fhir/StructureDefinition/translation"^^xsd:anyURI ;
    fhir:l <http://hl7.org/fhir/StructureDefinition/translation>         ]       ] )     ] ;
        ( fhir:designation [
    fhir:language [ fhir:v "de" ] ;
    fhir:value [ fhir:v "Empfehlungsgrad D" ]     ] )
      ] ) . #